RNAEditor

A tool to detect editing sites from deep sequencing data

RNAEditor is an all-in-one tool to analyze RNA editing events from RNA sequencing (RNA-seq) data. Raw sequencing reads (.fastq) or mapped reads (.bam) can be used as an input data. RNAEditor maps the reads to the genome, calculates sequence variations, filters for “non-editing sites” and applies a cluster algorithm to detect “editing islands”.

References

If you use RNAEditor in your work, please cite the following articles!
  • John D, Weirick T, Dimmeler S, Uchida S.
    RNAEditor: easy detection of RNA editing events and the introduction of editing islands.
    Briefings in Bioinformatics 2016. [PMID: 27694136]
  • Stellos K, Gatsiou A, Stamatelopoulos K, Matic LP, John D, ... Zeiher A & Dimmeler S
    Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation.
    Nature Medicine 2016. [PMID: 27595325]

News of RNAEditor